I'm not sure if I can explain it as well as Reed Richards could, but I'll give it a shot.

Anyway. The Malnosso is an organization that is apparently dedicated to "getting us home". They've trapped us in this enclosure, and occasionally they do these experiments which I believe they've stated is intended to help them get closer to that goal. The experiments that occur can range from a change of gender to altered memories, a change in appearance. I don't think there's much of a limit as to what sort of alterations could potentially happen to a person during these.